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Leukotriene B(4) receptor locus gene characterisation and association studies in asthma

BACKGROUND: Polymorphisms spanning genes involved in the production of leukotriene B(4) (LTB(4)) e.g. ALOX5AP and LTA4H are associated with asthma susceptibility, suggesting a role for LTB(4) in disease. The contribution of LTB(4)receptor polymorphism is currently unknown. The aim of this study was...

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Autors principals: Tulah, Asif S, Beghé, Bianca, Barton, Sheila J, Holloway, John W, Sayers, Ian
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607986/
https://ncbi.nlm.nih.gov/pubmed/23167751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-13-110
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