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Gene regulatory network analysis supports inflammation as a key neurodegeneration process in prion disease
BACKGROUND: The activation of immune cells in the brain is believed to be one of the earliest events in prion disease development, where misfolded PrionSc protein deposits are thought to act as irritants leading to a series of events that culminate in neuronal cell dysfunction and death. The role of...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607922/ https://ncbi.nlm.nih.gov/pubmed/23068602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-132 |
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