Mechanisms underlying regional differences in the Ca(2+) sensitivity of BK(Ca) current in arteriolar smooth muscle

β1-Subunits enhance the gating properties of large-conductance Ca(2+)-activated K(+) channels (BK(Ca)) formed by α-subunits. In arterial vascular smooth muscle cells (VSMCs), β1-subunits are vital in coupling SR-generated Ca(2+) sparks to BK(Ca) activation, affecting contractility and blood pressure...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yang, Yan, Sohma, Yoshiro, Nourian, Zahra, Ella, Srikanth R, Li, Min, Stupica, Aaron, Korthuis, Ronald J, Davis, Michael J, Braun, Andrew P, Hill, Michael A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2013
Pynciau:
Cardiovascular
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607871/
https://ncbi.nlm.nih.gov/pubmed/23297302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.241562
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