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Decreased activity of the smooth muscle Na(+)/Ca(2+) exchanger impairs arteriolar myogenic reactivity

Arteriolar myogenic vasoconstriction occurs when stretch or increased membrane tension leads to smooth muscle cell (SMC) depolarization and opening of voltage-gated Ca(2+) channels. While the mechanism underlying the depolarization is uncertain a role for non-selective cation channels has been demon...

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Detalhes bibliográficos
Main Authors: Raina, Hema, Ella, Srikanth R, Hill, Michael A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375699/
https://ncbi.nlm.nih.gov/pubmed/18218677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.150268
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