Telomerase Reverse Transcriptase (TERT) is a Therapeutic Target of Oleanane Triterpenoid CDDO-Me in Prostate Cancer

Methyl-2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate (CDDO-Me) is an synthetic oleanane triterpenoid with strong antiprolifertive and proapoptotic activities in cancer cells. However, the effect of CDDO-Me on human telomerase reverse transcriptase (hTERT) and its telomerase activity in prostate canc...

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Main Authors: Liu, Yongbo, Gao, Xiaohua, Deeb, Dorrah, Arbab, Ali S., Gautam, Subhash C.
格式: Artigo
語言:Inglês
出版: MDPI 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607816/
https://ncbi.nlm.nih.gov/pubmed/23519253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules171214795
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