Macrophage Migration Inhibitory Factor (MIF) Contributes to the Immune Escape of Ovarian Cancer by Downregulating NKG2D()

The pro-inflammatory cytokine macrophage migration inhibitory factor (MIF) stimulates tumor cell proliferation, migration and metastasis, promotes tumor angiogenesis, suppresses p53-mediated apoptosis and inhibits anti-tumor immunity by largely unknown mechanisms. We here describe an overexpression...

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Main Authors: Krockenberger, Mathias, Dombrowski, Yvonne, Weidler, Claudia, Ossadnik, Monika, Hönig, Arnd, Häusler, Sebastian, Voigt, Heike, Becker, Jürgen C., Leng, Lin, Steinle, Alexander, Weller, Michael, Bucala, Richard, Dietl, Johannes, Wischhusen, Jörg
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607742/
https://ncbi.nlm.nih.gov/pubmed/18490733
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