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Functional Characteristics of C-terminal Lysine to Cysteine Mutant Form of CTLA-4Ig
CTLA-4Ig is regarded as an inhibitory agent of the T cell proliferation via blocking the costimulatory signal which is essential for full T cell activation. To improve applicability, we developed the CTLA-4Ig-CTKC in which the c-terminal lysine had been replaced by cysteine through single amino acid...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Korean Association of Immunologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607706/ https://ncbi.nlm.nih.gov/pubmed/23559896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2013.13.1.16 |
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