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Copy choice mechanism of immunoglobulin heavy-chain switch recombination.
The immunoglobulin heavy-chain switch is mediated by a recombination event between DNA switch regions associated with donor and recipient constant-region genes. We have determined that the mutations which can be found in some switch regions after recombination appear to arise on only one strand of D...
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Main Authors: | , |
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Format: | Artigo |
Language: | Inglês |
Published: |
1990
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC360764/ https://ncbi.nlm.nih.gov/pubmed/2104661 |
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