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Empirical null distribution based modeling of multi-class differential gene expression detection

In this paper, we study the multi-class differential gene expression detection for microarray data. We propose a likelihood based approach to estimating an empirical null distribution to incorporate gene interactions and provide more accurate false positive control than the commonly used permutation...

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Autors principals: Cao, Xiting, Wu, Baolin, Hertz, Marshall I.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607635/
https://ncbi.nlm.nih.gov/pubmed/23538964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02664763.2012.743976
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