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On the geometric modeling approach to empirical null distribution estimation for empirical Bayes modeling of multiple hypothesis testing

We study the geometric modeling approach to estimating the null distribution for the empirical Bayes modeling of multiple hypothesis testing. The commonly used method is a nonparametric approach based on the Poisson regression, which however could be unduly affected by the dependence among test stat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Wu, Baolin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580033/
https://ncbi.nlm.nih.gov/pubmed/23314152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compbiolchem.2012.12.001
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