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On the geometric modeling approach to empirical null distribution estimation for empirical Bayes modeling of multiple hypothesis testing
We study the geometric modeling approach to estimating the null distribution for the empirical Bayes modeling of multiple hypothesis testing. The commonly used method is a nonparametric approach based on the Poisson regression, which however could be unduly affected by the dependence among test stat...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580033/ https://ncbi.nlm.nih.gov/pubmed/23314152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compbiolchem.2012.12.001 |
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