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Suppression of Core 1 Gal-Transferase Is Associated with Reduction of TF and Reciprocal Increase of Tn, sialyl-Tn and Core 3 Glycans in Human Colon Cancer Cells
It has long been presumed, though with surprisingly little evidence, a competition between Core 1 Gal-transferase (C1GalT), Core 3 GlcNAc-transferase (C3GnT) and sialyl-transferase (ST6GalNAc-T) for elongation of O-linked mucin-type glycans initiated with GalNAcα-Ser/Thr. This study tested this pres...
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Main Authors: | , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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Public Library of Science
2013
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607565/ https://ncbi.nlm.nih.gov/pubmed/23536887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059792 |
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