Conversion of the lac repressor into an allosterically regulated transcriptional activator for mammalian cells.
A novel mammalian regulatory system was created by using the Escherichia coli lac repressor. The lac repressor was converted into a mammalian transcriptional activator by modifying the lac repressor coding region to include a nuclear localization signal from the simian virus 40 (SV40) large tumor an...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2162473/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.7.3343-3356.1990 |
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