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Effects of tumor irradiation on host T regulatory cells and systemic immunity in the context of adoptive T cell therapy in mice

In this study, we employed a murine D5 melanoma model to study the effects of local tumor irradiation on the therapeutic efficacy of adoptive T cell therapy. Tumor irradiation was delivered in 5 daily fractions (8.5 Gy) to s.c. tumors on days 7-11 after tumor inoculation. After the last radiation do...

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Detalhes bibliográficos
Main Authors: Wei, Shuang, Egenti, Martin U., Teitz-Tennenbaum, Seagal, Zou, Weiping, Chang, Alfred E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607501/
https://ncbi.nlm.nih.gov/pubmed/23377667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31828298e6
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