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PRP18, a protein required for the second reaction in pre-mRNA splicing.
We have investigated the role of a novel temperature-sensitive splicing mutation, prp18. We had previously demonstrated that an accumulation of the lariat intermediate of splicing occurred at the restrictive temperature in vivo. We have now used the yeast in vitro splicing system to show that extrac...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1990
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC360747/ https://ncbi.nlm.nih.gov/pubmed/2403639 |
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