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Rho GTPases and their roles in cancer metabolism
Recently, the small molecule 968 was found to block the Rho GTPase-dependent growth of cancer cells in cell culture and mouse xenografts, and when the target of 968 was found to be mitochondrial enzyme glutaminase (GLS1) it revealed a surprising link between Rho GTPases and mitochondrial glutamine m...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607349/ https://ncbi.nlm.nih.gov/pubmed/23219172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2012.10.011 |
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