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RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells
Vesicular structures called microvesicles (MV) that are shed from the surfaces of cancer cells are capable of transferring oncogenic cargo to recipient cancer cells, as well as to normal cells, sending mitogenic signals that greatly enhance tumor growth. Because MVs are stable in the circulation, th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607381/ https://ncbi.nlm.nih.gov/pubmed/22266864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.636 |
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