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A Novel N-terminal Motif of Dipeptidyl Peptidase-like Proteins Produces Rapid Inactivation of Kv4.2 Channels by a Pore-blocking Mechanism

The somatodendritic subthreshold A-type K(+) current in neurons (I(SA)) depends on its kinetic and voltage-dependent properties to regulate membrane excitability, action potential repetitive firing, and signal integration. Key functional properties of the Kv4 channel complex underlying I(SA) are det...

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Main Authors: Jerng, Henry H., Dougherty, Kevin, Covarrubias, Manuel, Pfaffinger, Paul J.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607289/
https://ncbi.nlm.nih.gov/pubmed/19901547
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