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The role of nitric oxide on DNA damage induced by benzene metabolites

Benzene, a tobacco constituent, is a leukemogen in humans and a carcinogen in rodents. Several benzene metabolites generate superoxide anion (O(2)(•−)) and induce nitric oxide synthase in the bone marrow of mice. We hypothesized that the reaction of nitric oxide ((•)NO) with O(2)(•−) leads to the fo...

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Bibliografiske detaljer
Main Authors: MELIKIAN, ASSIEH A., CHEN, KUN-MING, LI, HEYI, SODUM, RAMA, FIALA, EMERICH, EL-BAYOUMY, KARAM
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607205/
https://ncbi.nlm.nih.gov/pubmed/18425395
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