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The evolutionary significance of certain amino acid substitutions and their consequences for HIV-1 immunogenicity toward HLA's A*0201 and B*27

In silico tools are employed to examine the evolutionary relationship to possible vaccine peptide candidates' development. This perspective sheds light on the proteomic changes affecting the creation of HLA specific T-cell stimulating peptide vaccines for HIV. Full-length sequences of the envel...

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Detalhes bibliográficos
Main Authors: Hecht, Luke, Dormer, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607191/
https://ncbi.nlm.nih.gov/pubmed/23745018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630009315
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