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Galantamine potentiates the neuroprotective effect of memantine against NMDA-induced excitotoxicity

The combination of memantine, an N-methyl-d-aspartate (NMDA) receptor antagonist, with an acetylcholinesterase inhibitor (AChEI) is the current standard of care in Alzheimer's disease (AD). Galantamine, an AChEI currently marketed for the treatment of AD, exerts memory-enhancing and neuroprotec...

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Autors principals: Lopes, João P, Tarozzo, Glauco, Reggiani, Angelo, Piomelli, Daniele, Cavalli, Andrea
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607148/
https://ncbi.nlm.nih.gov/pubmed/23532860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.118
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