Galantamine potentiates the neuroprotective effect of memantine against NMDA-induced excitotoxicity

The combination of memantine, an N-methyl-d-aspartate (NMDA) receptor antagonist, with an acetylcholinesterase inhibitor (AChEI) is the current standard of care in Alzheimer's disease (AD). Galantamine, an AChEI currently marketed for the treatment of AD, exerts memory-enhancing and neuroprotec...

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Bibliografiske detaljer
Main Authors: Lopes, João P, Tarozzo, Glauco, Reggiani, Angelo, Piomelli, Daniele, Cavalli, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607148/
https://ncbi.nlm.nih.gov/pubmed/23532860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.118
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