Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity

GATA binding protein 3 (Gata3) is a GATA family transcription factor that controls differentiation of naïve CD4 T cells into T helper 2 (Th2) cells. However, it is unknown how Gata3 simultaneously activates Th2-specific genes while repressing those of other Th lineages. Here we show that chromodomai...

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Hlavní autoři: Hosokawa, Hiroyuki, Tanaka, Tomoaki, Suzuki, Yutaka, Iwamura, Chiaki, Ohkubo, Shuichi, Endoh, Kanji, Kato, Miki, Endo, Yusuke, Onodera, Atsushi, Tumes, Damon John, Kanai, Akinori, Sugano, Sumio, Nakayama, Toshinori
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606997/
https://ncbi.nlm.nih.gov/pubmed/23471993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220865110
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