The 1p13.3 LDL (C)-Associated Locus Shows Large Effect Sizes in Young Populations

Genome-wide association studies (GWAS) have identified polymorphic loci associated with coronary artery disease (CAD) risk factors (i. e. serum lipids) in adult populations (42–69 yrs). We hypothesized that younger populations would show a greater relative genetic component due to fewer confounding...

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Autors principals: Devaney, Joseph M., Thompson, Paul D., Visich, Paul S., Saltarelli, William A., Gordon, Paul M., Orkunoglu-Suer, E. Funda, Gordish-Dressman, Heather, Harmon, Brennan T., Bradbury, Margaret K., Panchapakesan, Karuna, Khianey, Rahul, Hubal, Monica J., Clarkson, Priscilla M., Pescatello, Linda S., Zoeller, Robert F., Moyna, Niall M., Angelopoulos, Theodore J., Kraus, William E., Hoffman, Eric P.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606915/
https://ncbi.nlm.nih.gov/pubmed/21297524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e3182139227
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