Tregs are Dysfunctional in Vivo in a Spontaneous Murine Model of Crohn’s Disease

Although regulatory T cells (Tregs) have been implicated in inflammatory bowel disease (IBD), Tregs from Crohn’s disease (CD) patients are increased in number and function normally in vitro. To clarify this disparity, we studied Treg function in vivo using a spontaneous model of CD-like ileitis. We...

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Autori principali: Ishikawa, Dai, Okazawa, Akira, Corridoni, Daniele, Jia, Li Guo, Wang, Ziao Ming, Xin, Wei, Arseneau, Kristen O., Pizarro, Theresa T., Cominelli, Fabio
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606708/
https://ncbi.nlm.nih.gov/pubmed/22785225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.67
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