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Tregs are Dysfunctional in Vivo in a Spontaneous Murine Model of Crohn’s Disease
Although regulatory T cells (Tregs) have been implicated in inflammatory bowel disease (IBD), Tregs from Crohn’s disease (CD) patients are increased in number and function normally in vitro. To clarify this disparity, we studied Treg function in vivo using a spontaneous model of CD-like ileitis. We...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606708/ https://ncbi.nlm.nih.gov/pubmed/22785225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.67 |
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