Tregs are Dysfunctional in Vivo in a Spontaneous Murine Model of Crohn’s Disease

Although regulatory T cells (Tregs) have been implicated in inflammatory bowel disease (IBD), Tregs from Crohn’s disease (CD) patients are increased in number and function normally in vitro. To clarify this disparity, we studied Treg function in vivo using a spontaneous model of CD-like ileitis. We...

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Autores principales: Ishikawa, Dai, Okazawa, Akira, Corridoni, Daniele, Jia, Li Guo, Wang, Ziao Ming, Xin, Wei, Arseneau, Kristen O., Pizarro, Theresa T., Cominelli, Fabio
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606708/
https://ncbi.nlm.nih.gov/pubmed/22785225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.67
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