Tregs are Dysfunctional in Vivo in a Spontaneous Murine Model of Crohn’s Disease

Although regulatory T cells (Tregs) have been implicated in inflammatory bowel disease (IBD), Tregs from Crohn’s disease (CD) patients are increased in number and function normally in vitro. To clarify this disparity, we studied Treg function in vivo using a spontaneous model of CD-like ileitis. We...

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Main Authors: Ishikawa, Dai, Okazawa, Akira, Corridoni, Daniele, Jia, Li Guo, Wang, Ziao Ming, Xin, Wei, Arseneau, Kristen O., Pizarro, Theresa T., Cominelli, Fabio
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606708/
https://ncbi.nlm.nih.gov/pubmed/22785225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.67
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