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Transgenic sheep generated by lentiviral vectors: safety and integration analysis of surrogates and their offspring
The safety of HIV-1 based vectors was evaluated during the production of transgenic sheep. Vectors were introduced into the perivitelline space of in vivo derived one-cell sheep embryos by microinjection then transferred into the oviducts of recipient females. At 60–70 days of gestation, a portion o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606283/ https://ncbi.nlm.nih.gov/pubmed/23180364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-012-9674-3 |
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