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Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening

DNA sliding clamps form an oligomeric ring encircling DNA and serve as a moving platform for DNA-processing proteins. The opening and closing of a sliding-clamp ring is essential to load the clamp onto DNA in order to perform its functions. The molecular details of how clamp rings open and enclose D...

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Autors principals: Hlinkova, Vladena, Xing, Guangxin, Bauer, Jacob, Shin, Yoon Jung, Dionne, Isabelle, Rajashankar, Kanagalaghatta R., Bell, Stephen D., Ling, Hong
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606083/
https://ncbi.nlm.nih.gov/pubmed/18703842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444908021665
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