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Characterization of an archaeal family 4 uracil DNA glycosylase and its interaction with PCNA and chromatin proteins

We describe the characterization of a family 4 UDG1 (uracil DNA glycosylase) from the crenarchaeote Sulfolobus solfataricus. UDG1 is found to have a marked preference for substrates containing a G:U base pair over either A:U or single-stranded uracil-containing DNA substrates. UDG1 is found to inter...

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Main Authors: Dionne, Isabelle, Bell, Stephen D.
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135018/
https://ncbi.nlm.nih.gov/pubmed/15588253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041661
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