NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis

Neuropilin (NRP) 1 is a receptor for the vascular endothelial growth factor (VEGF)-A and is essential for normal angiogenesis. Previous in vitro experiments identified NRP1 interactions with VEGF-A’s main signaling receptor VEGFR2 within endothelial cells, but also between nonendothelial NRP1 and en...

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Autors principals: Fantin, Alessandro, Vieira, Joaquim M., Plein, Alice, Denti, Laura, Fruttiger, Marcus, Pollard, Jeffrey W., Ruhrberg, Christiana
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2013
Matèries:
Vascular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606070/
https://ncbi.nlm.nih.gov/pubmed/23315162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-424713
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