Mutational activation of c-raf-1 and definition of the minimal transforming sequence.
A series of wild-type and mutant raf genes was transfected into NIH 3T3 cells and analyzed for transforming activity. Full-length wild-type c-raf did not show transforming activity. Two types of mutations resulted in oncogenic activity similar to that of v-raf: truncation of the amino-terminal half...
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| Опубліковано в:: | Mol Cell Biol |
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| Автори: | , , , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Taylor & Francis
1990
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2188091/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.6.2503-2512.1990 |
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