Role of the pituitary–adrenal axis in granulocyte-colony stimulating factor-induced neuroprotection against hypoxia–ischemia in neonatal rats

Several reports indicate that the activity of the hypothalamic–pituitary–adrenal axis (HPA) is increased after a brain insult and that its down-regulation can improve detrimental outcomes associated with ischemic brain injuries. Granulocyte-colony stimulating factor (G-CSF) is a neuroprotective drug...

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Hlavní autoři: Charles, Mélissa S., Ostrowski, Robert P., Manaenko, Anatol, Duris, Kamil, Zhang, John H., Tang, Jiping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606051/
https://ncbi.nlm.nih.gov/pubmed/22779090
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