Llwytho...
Zic3 is required in the extra-cardiac perinodal region of the lateral plate mesoderm for left–right patterning and heart development
Mutations in ZIC3 cause human X-linked heterotaxy and isolated cardiovascular malformations. A mouse model with targeted deletion of Zic3 demonstrates an early role for Zic3 in gastrulation, CNS, cardiac and left–right axial development. The observation of multiple malformations in Zic3(null) mice a...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
2013
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606008/ https://ncbi.nlm.nih.gov/pubmed/23184148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds494 |
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