Cell-specific toxicity of a chimeric protein composed of interleukin-6 and Pseudomonas exotoxin (IL6-PE40) on tumor cells.

IL6-PE40 is a chimeric toxin composed of human interleukin-6 (IL6) linked by a peptide bond to PE40, a form of Pseudomonas exotoxin (PE) devoid of its cell recognition domain. To identify cancer cell lines with high numbers of IL6 receptors and to assess the usefulness of IL6-PE40 as a possible anti...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Siegall, C B, Nordan, R P, FitzGerald, D J, Pastan, I
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 1990
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2160579/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.6.2443-2447.1990
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