Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier

Cardiac triacylglycerol (TG) catabolism critically depends on the TG hydrolytic activity of adipose triglyceride lipase (ATGL). Perilipin 5 (Plin5) is expressed in cardiac muscle (CM) and has been shown to interact with ATGL and its coactivator comparative gene identification-58 (CGI-58). Furthermor...

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Bibliografische gegevens
Hoofdauteurs: Pollak, Nina M., Schweiger, Martina, Jaeger, Doris, Kolb, Dagmar, Kumari, Manju, Schreiber, Renate, Kolleritsch, Stephanie, Markolin, Philipp, Grabner, Gernot F., Heier, Christoph, Zierler, Kathrin A., Rülicke, Thomas, Zimmermann, Robert, Lass, Achim, Zechner, Rudolf, Haemmerle, Guenter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2013
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605985/
https://ncbi.nlm.nih.gov/pubmed/23345410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M034710
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