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Optimization of Data-Dependent Acquisition Parameters for Coupling High-Speed Separations with LC-MS/MS for Protein Identifications

Recent developments in chromatography, such as ultra-HPLC and superficially porous particles, offer significantly improved peptide separation. The narrow peak widths, often only several seconds, can permit a 15-min liquid chromatography run to have a similar peak capacity as a 60-min run using tradi...

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Autors principals: Johnson, Darryl, Boyes, Barry, Fields, Taylor, Kopkin, Rachel, Orlando, Ron
Format: Artigo
Idioma:Inglês
Publicat: Association of Biomolecular Resource Facilities 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605922/
https://ncbi.nlm.nih.gov/pubmed/23814498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7171/jbt.13-2402-003
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