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Notoginsenoside R1 attenuates cardiac dysfunction in endotoxemic mice: an insight into oestrogen receptor activation and PI3K/Akt signalling

BACKGROUND AND PURPOSE: Notoginsenoside R1 (NG-R1), a novel phytoestrogen isolated from Panax notoginseng, is believed to have anti-inflammatory, anti-oxidative and anti-apoptotic properties. However, its cardioprotective properties and underlying mechanisms are largely unknown. Here we have assesse...

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Detalhes bibliográficos
Main Authors: Sun, Bing, Xiao, Jing, Sun, Xiao-Bo, Wu, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605881/
https://ncbi.nlm.nih.gov/pubmed/23170834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12063
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