Notoginsenoside R1 attenuates glucose-induced podocyte injury via the inhibition of apoptosis and the activation of autophagy through the PI3K/Akt/mTOR signaling pathway

Injury to terminally differentiated podocytes contributes ignificantly to proteinuria and glomerulosclerosis. The aim of this study was to examine the protective effects of notoginsenoside R1 (NR1) on the maintenance of podocyte number and foot process architecture via the inhibition of apoptosis, t...

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Publicado no:Int J Mol Med
Main Authors: Huang, Guodong, Zou, Bingyu, Lv, Jianzhen, Li, Tongyu, Huai, Guoli, Xiang, Shaowei, Lu, Shilong, Luo, Huan, Zhang, Yaping, Jin, Yi, Wang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360354/
https://ncbi.nlm.nih.gov/pubmed/28112381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.2864
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