Ruthenium Red Colorimetric and Birefringent Staining of Amyloid-β Aggregates in Vitro and in Tg2576 Mice

[Image: see text] Alzheimer’s disease (AD) is a devastating neurodegenerative disease most notably characterized by the misfolding of amyloid-β (Aβ) into fibrils and its accumulation into plaques. In this Article, we utilize the affinity of Aβ fibrils to bind metal cations and subsequently imprint t...

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Hauptverfasser: Cook, Nathan P., Archer, Clarissa M., Fawver, Janelle N., Schall, Hayley E., Rodriguez-Rivera, Jennifer, Dineley, Kelly T., Martí, Angel A., Murray, Ian V. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2012
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605823/
https://ncbi.nlm.nih.gov/pubmed/23509974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300219n
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