Dentin Phosphophoryn Activates Smad Protein Signaling through Ca(2+)-Calmodulin-dependent Protein Kinase II in Undifferentiated Mesenchymal Cells

Dentin phosphophoryn (DPP) is a major noncollagenous protein in the dentin matrix. In this study, we demonstrate that pluripotent stem cells such as C3H10T1/2 and human bone marrow cells can be committed to the osteogenic lineage by DPP. Treatment with DPP can stimulate the release of intracellular...

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Hlavní autoři: Eapen, Asha, Kulkarni, Roma, Ravindran, Sriram, Ramachandran, Amsaveni, Sundivakkam, Premanand, Tiruppathi, Chinnaswammy, George, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605677/
https://ncbi.nlm.nih.gov/pubmed/23362283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413997
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