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Dentin Phosphoprotein (DPP) Activates Integrin-mediated Anchorage-dependent Signals in Undifferentiated Mesenchymal Cells

Dentin phosphoprotein (DPP), a major noncollagenous protein of the dentin matrix, is a highly acidic protein that binds Ca(2+) avidly and is thus linked to matrix mineralization. Here, we demonstrate that the RGD domain in DPP can bind to integrins on the cell surface of undifferentiated mesenchymal...

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Bibliographic Details
Main Authors: Eapen, Asha, Ramachandran, Amsaveni, George, Anne
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285302/
https://ncbi.nlm.nih.gov/pubmed/22134916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.290080
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