Mechanisms of Action of Hormone-sensitive Lipase in Mouse Leydig Cells: ITS ROLE IN THE REGULATION OF THE STEROIDOGENIC ACUTE REGULATORY PROTEIN

Hormone-sensitive lipase (HSL) catalyzes the hydrolysis of cholesteryl esters in steroidogenic tissues and, thus, facilitates cholesterol availability for steroidogenesis. The steroidogenic acute regulatory protein (StAR) controls the rate-limiting step in steroid biosynthesis. However, the modes of...

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Bibliographic Details
Main Authors: Manna, Pulak R., Cohen-Tannoudji, Joëlle, Counis, Raymond, Garner, Charles W., Huhtaniemi, Ilpo, Kraemer, Fredric B., Stocco, Douglas M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605665/
https://ncbi.nlm.nih.gov/pubmed/23362264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.417873
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