SET Protein Interacts with Intracellular Domains of the Gonadotropin-releasing Hormone Receptor and Differentially Regulates Receptor Signaling to cAMP and Calcium in Gonadotrope Cells

In mammals, the receptor of the neuropeptide gonadotropin-releasing hormone (GnRHR) is unique among the G protein-coupled receptor (GPCR) family because it lacks the carboxyl-terminal tail involved in GPCR desensitization. Therefore, mechanisms involved in the regulation of GnRHR signaling are curre...

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Detalhes bibliográficos
Main Authors: Avet, Charlotte, Garrel, Ghislaine, Denoyelle, Chantal, Laverrière, Jean-Noël, Counis, Raymond, Cohen-Tannoudji, Joëlle, Simon, Violaine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554931/
https://ncbi.nlm.nih.gov/pubmed/23233674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.388876
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