Sarco(endo)plasmic Reticulum Calcium ATPase (SERCA) Inhibition by Sarcolipin Is Encoded in Its Luminal Tail

The sarco(endo)plasmic reticulum calcium ATPase (SERCA) is regulated in a tissue-dependent manner via interaction with the short integral membrane proteins phospholamban (PLN) and sarcolipin (SLN). Although defects in SERCA activity are known to cause heart failure, the regulatory mechanisms imposed...

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Main Authors: Gorski, Przemek A., Glaves, John Paul, Vangheluwe, Peter, Young, Howard S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Membrane Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605661/
https://ncbi.nlm.nih.gov/pubmed/23362265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.446161
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