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Towards a universal vaccine for avian influenza: Protective efficacy of modified Vaccinia virus Ankara and Adenovirus vaccines expressing conserved influenza antigens in chickens challenged with low pathogenic avian influenza virus

Current vaccines targeting surface proteins can drive antigenic variation resulting either in the emergence of more highly pathogenic viruses or of antigenically distinct viruses that escape control by vaccination and thereby persist in the host population. Influenza vaccines typically target the hi...

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Detalhes bibliográficos
Main Authors: Boyd, Amy C., Ruiz-Hernandez, Raul, Peroval, Marylene Y., Carson, Connor, Balkissoon, Devanand, Staines, Karen, Turner, Alison V., Hill, Adrian V.S., Gilbert, Sarah C., Butter, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605591/
https://ncbi.nlm.nih.gov/pubmed/23200938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.11.047
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