The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity.

We have isolated the gene for a novel growth regulator, amphiregulin (AR), that is evolutionarily related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). AR is a bifunctional growth modulator: it interacts with the EGF/TGF-alpha receptor to promote the growth of no...

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Autors principals: Plowman, G D, Green, J M, McDonald, V L, Neubauer, M G, Disteche, C M, Todaro, G J, Shoyab, M
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC360543/
https://ncbi.nlm.nih.gov/pubmed/2325643
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