The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity.

We have isolated the gene for a novel growth regulator, amphiregulin (AR), that is evolutionarily related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). AR is a bifunctional growth modulator: it interacts with the EGF/TGF-alpha receptor to promote the growth of no...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Plowman, G D, Green, J M, McDonald, V L, Neubauer, M G, Disteche, C M, Todaro, G J, Shoyab, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1990
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2325643/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.5.1969-1981.1990
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