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Dendritic Cell-induced Activation of Latent HIV-1 Provirus in Actively Proliferating Primary T Lymphocytes

HIV-1 latency remains a formidable barrier towards virus eradication as therapeutic attempts to purge these reservoirs are so far unsuccessful. The pool of transcriptionally silent proviruses is established early in infection and persists for a lifetime, even when viral loads are suppressed below de...

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Detalhes bibliográficos
Main Authors: van der Sluis, Renée M., van Montfort, Thijs, Pollakis, Georgios, Sanders, Rogier W., Speijer, Dave, Berkhout, Ben, Jeeninga, Rienk E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605277/
https://ncbi.nlm.nih.gov/pubmed/23555263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003259
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