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The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors.

Signalling proteins such as phospholipase C-gamma (PLC-gamma) or GTPase-activating protein (GAP) of ras contain conserved regions of approximately 100 amino acids termed src homology 2 (SH2) domains. SH2 domains were shown to be responsible for mediating association between signalling proteins and t...

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Библиографические подробности
Главные авторы: Li, W, Hu, P, Skolnik, E Y, Ullrich, A, Schlessinger, J
Формат: Artigo
Язык:Inglês
Опубликовано: 1992
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC360522/
https://ncbi.nlm.nih.gov/pubmed/1333047
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